PCOS: The Role of Insulin Resistance and Inflammation

Polycystic ovarian syndrome (PCOS) is the one of the most common causes of anovulation in reproductive age women. Due to PCOS’s complexity and different phenotypes, diagnosis and treatment modalities may be delayed. In addition, PCOS has been associated with higher rates of recurrent pregnancy loss, gestational diabetes associated with the development of metabolic syndrome. In addition to the known role of insulin resistance, increasing data has reported an association with inflammatory markers that affect negatively affect pregnancy and long term health. The lecture will address diagnosis and treatment for PCOS patients. Discuss the role of insulin resistance and inflammation on ovulation, implantation, recurrent pregnancy loss and development of metabolic syndrome

Learning Objectives:

  • Describe the clinical features of PCOS and eliciting a pertinent history.
  • Interpretation of selected test to confirm the diagnosis of PCOS.
  • Review medical treatment as well as alternative therapies for PCOS.
  • Discuss long term follow up to decrease the risk of cancer, cardiovascular disease and metabolic syndrome.

IFS from June 12, 2016

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